Hexachlorobenzene (HCB), as one of the persistent organic pollutants (POPs) and possible human carcinogens, particularly resistant to biodegradation. In this study, HcbA1A3, a different flavin-N5-peroxide using enzymes and the only known naturally aerobic dechlorinase HCB, the biochemical marked.
Its clear preference for HCB in the binding affinity of sets that can only oxidize HcbA1 HCB than less chlorinated benzene as pentachlorobenzene and tetrachlorobenzenes. In addition, the crystal structure and complex HcbA1 with FMN resolved, revealing HcbA1 as new members of the bacterial luciferase-like family. Compared with a close homolog, the substrate binding pocket is much smaller than HcbA1 show limited space requirements for catalysis.
In the midst of an active, Tyr362 and Asp315 necessary in maintaining a normal conformation HcbA1, while Arg311, Arg314, Phe10, Val59 and Met12 is important for substrate affinity. They should have a place in the productive orientation HCB through multiple interactions. His17, with close contact with the oxidation locations HCB, possibly targeting the improvement of chlorine atoms and stabilizing the reaction intermediates.
Enzymatic characteristics and crystal structures reported here provide new insights into the substrate specificity and catalytic mechanism HcbA1, which opens the way for rational engineering and applications in bioremediation of polluted HCB environments.IMPORTANCE As an endocrine disruptor and possible carcinogen to humans, hexachlorobenzene (HCB) is resistant to biodegradation, largely due to difficulties in dechlorination.
Lack of knowledge to dechlorinases HCB limit their application in bioremediation. More recently, a HcbA1A3 monooxygenases reported HCB, which is the only known naturally aerobic HCB dechlorinase so far. Here we report the biochemical and structural characterization, which provides new insight into the substrate selectivity and catalytic mechanism. The study also improve our understanding of dechlorinases HCB and flavin-N5-peroxide using enzymes.
Ensuring the biochemical function of pectin methylesterase important in microbial gut Bacteroides thetaiotaomicron
Pectin is a major food source of nutrients for the human intestinal microbiota (HGM). Bacteroides thetaiotaomicron protruding gut microbes was recently shown to encode a founding member of (BT1017) of a new family of pectin methylesterases (PMEs) important for the metabolism of pectin complex rhamnogalacturonan-II (RG-II).
However, the biochemical and structural knowledge of this family less. Here, we show that the BT1017 is very important for the metabolism of a ΔBT1017oligoB oligosaccharides derived RG-II produced by BT1017 deletion mutant (ΔBT1017) during growth on carbohydrate extract of apple juice.
ΔBT1017oligoB structural analysis using a combination of enzymatic, mass spectrometry and nuclear magnetic resonance approach to reveal that it was a lady-oligosaccharides bi-methylated GlcA-β1,4- (2-O-Me-Xyl-α1,3) -Fuc- α1,4- (gALA-β1,3) -Rha-α1,3-Fire-β1,2- (Araf-α1,3) – (gala-α1,4) -GalA component containing RG-II backbones and side chains. We show that the catalytic module BT1017 adopt an alpha / beta (α / β) hydrolase fold, which consists of 10 twisted β-sheet strand middle sandwiched by multiple α-helices. It is a new fold for PMEs, which is dominated by left-handed β-helix proteins.
Bioinformatics analysis revealed that the family is dominated by a sequence of genera protruding from HGM, including Bacteroides and Prevotella Our results not only highlight the important role played by this family of enzymes in the metabolism of pectin but give new insights into the molecular basis of adaptation B. thetaiotaomicron to gut human.
Cellular and biochemical mechanisms of meroterpenoid Oncocalyxone antileukemic A
Oncocalyxone A, 1,4-benzokuinon derived from Cordia oncocalyx, showed anti-inflammatory, antimicrobial and anti-diabetic. The purpose of this study was to (1) examine the cytotoxic action oncocalyxone A on normal and tumor cell lines of human and (2) determine the mechanistic action effects on leukemia cells using the technique of the underlying cellular and molecular.
Antiproliferative studies on cancer cell lines, cells of peripheral blood mononuclear cells, and human erythrocytes done using colorimetric tests. To understand cytotoxicity, an assessment carried out by the HL-60 leukemia cells (8, 16.5, or 33 M) after 24 h incubation by using light and fluorescence microscopy, trypan blue, cytometry, Comet assay, western blot caspases and poly-ADP- flow ribose polymerase (PARP), and the effect on topoisomerase I and II. A Oncocalyxone exhibited cytotoxic action in HL-60 cells and dividing leukocytes, but minimal hemolytic action on erythrocytes.
The mechanistic investigation showed a decrease in cell viability, loss of membrane integrity, cells shrink, chromatin condensation, blebbings, phosphatidylserine externalization, caspase activation, PARP cleavage, mitochondrial depolarization and DNA damage. Pre-treatment with N-acetylcysteine 4 mM significantly reduced DNA damage and prevent the loss of membrane integrity. Oncocalyxone A free radical activity depends shown antileukemic through apoptosis and DNA damage induced in HL-60 cells.
Oncocalyxone A has a chemical structural simplicity allows it to be a cost-effective alternative. These properties justify further improvements to improve the activity and selectivity and pharmaceutical formulation development. Abbreviations Acridine orange, AO; ANOVA, analysis of variance; BSA, bovine serum albumin; IN, Damage Index; DMSO, Dimethylsulfoxide; EC50, the effective concentration of 50%; EDTA, ethylenediamine tetraacetic acid; EB, ethidium bromide; HCT-116, colon carcinoma lines; HL-60, promyelocytic leukemia line; IC50, 50% inhibitory concentration; MTT, 3- (4,5-dimethyl-2-thiazolyl) -2,5-diphenyl-2H-tetrazolium bromide; OVCAR-8 ovarian carcinoma line; NAC, N-acetylcysteine, PBMC, peripheral blood mononuclear cells; PBS, phosphate-buffered saline; PI, propidium iodide; PARP, poly-ADP-ribose polymerase; RPMI-1640 media Roswell Park Memorial Institute; SF-295 glioblastoma line; ROS, reactive oxygen species; 7-AAD, 7-amino-aktinomisin D; H2-DCF-DA, 7′-dichlorodihydrofluorescein diacetate.
Biochemistry and in silico identification of the active site and catalytic mechanisms of circadian HESPERIN deadenylase
24h a molecular clock based on the stability of the transcript rhythmic disclosed. Shortening of the poly (A) tail of the mRNA is often the first step and the rate-limiting determine the life span of mRNA and catalyzed by deadenylases.
Here, we determine the catalytic site Hesperin, a circadian deadenylase recently described in plants, using a modified site-directed mutagenesis protocols and custom vectors, pATHRA. To explore the catalytic efficiency of AtHESPERIN we examined the effect of AMP and neomycin, and used molecular modeling simulations to propose a catalytic mechanism.
Collectively, biochemistry and classify AtHESPERIN silico results in EEP deadenylase superfamily and contribute to the understanding of the complex mechanisms of circadian mRNA turnover.
 ELISA Kit) Mouse Arachidonate-5-Lipoxygenase (ALOX5) ELISA Kit |
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| RD-ALOX5-Mu-48Tests | Reddot Biotech | 48 Tests | EUR 511 |
Mouse Arachidonate-5-Lipoxygenase (ALOX5) ELISA Kit |
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| RD-ALOX5-Mu-96Tests | Reddot Biotech | 96 Tests | EUR 709 |
 ELISA Kit) Rat Arachidonate-5-Lipoxygenase (ALOX5) ELISA Kit |
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| RD-ALOX5-Ra-48Tests | Reddot Biotech | 48 Tests | EUR 534 |
Rat Arachidonate-5-Lipoxygenase (ALOX5) ELISA Kit |
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| RD-ALOX5-Ra-96Tests | Reddot Biotech | 96 Tests | EUR 742 |
 ELISA Kit) Human Arachidonate-5-Lipoxygenase (ALOX5) ELISA Kit |
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| RDR-ALOX5-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 522 |
Human Arachidonate-5-Lipoxygenase (ALOX5) ELISA Kit |
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| RDR-ALOX5-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 724 |
Mouse Arachidonate-5-Lipoxygenase (ALOX5) ELISA Kit |
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| RDR-ALOX5-Mu-48Tests | Reddot Biotech | 48 Tests | EUR 534 |
Mouse Arachidonate-5-Lipoxygenase (ALOX5) ELISA Kit |
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| RDR-ALOX5-Mu-96Tests | Reddot Biotech | 96 Tests | EUR 742 |
Rat Arachidonate-5-Lipoxygenase (ALOX5) ELISA Kit |
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| RDR-ALOX5-Ra-48Tests | Reddot Biotech | 48 Tests | EUR 558 |
Rat Arachidonate-5-Lipoxygenase (ALOX5) ELISA Kit |
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| RDR-ALOX5-Ra-96Tests | Reddot Biotech | 96 Tests | EUR 776 |
 ALOX5 antibody |
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| 70R-33363 | Fitzgerald | 100 ug | EUR 327 |
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Description: Rabbit polyclonal ALOX5 antibody |
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 ALOX5 Antibody |
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| ABD6881 | Lifescience Market | 100 ug | EUR 438 |
ALOX5 antibody |
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| 70R-14181 | Fitzgerald | 100 ug | EUR 322 |
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Description: Affinity purified Rabbit polyclonal ALOX5 antibody |
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ALOX5 antibody |
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| 70R-15688 | Fitzgerald | 50 ul | EUR 435 |
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Description: Rabbit polyclonal ALOX5 antibody |
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ALOX5 Antibody |
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| DF6881 | Affbiotech | 200ul | EUR 304 |
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Description: ALOX5 Antibody detects endogenous levels of total ALOX5. |
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ALOX5 Antibody |
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| 1-CSB-PA043268 | Cusabio |
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Description: A polyclonal antibody against ALOX5. Recognizes ALOX5 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:500-1:5000, IHC:1:50-1:150 |
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ALOX5 Antibody |
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| 1-CSB-PA008474 | Cusabio |
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Description: A polyclonal antibody against ALOX5. Recognizes ALOX5 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/10000 |
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ALOX5 Antibody |
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| 1-CSB-PA001624GA01HU | Cusabio |
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Description: A polyclonal antibody against ALOX5. Recognizes ALOX5 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, IF |
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ALOX5 Antibody |
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| 1-CSB-PA001624LA01HU | Cusabio |
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Description: A polyclonal antibody against ALOX5. Recognizes ALOX5 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200 |
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ALOX5 Antibody |
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| 1-CSB-PA787659 | Cusabio |
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Description: A polyclonal antibody against ALOX5. Recognizes ALOX5 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:500-1:2000, IHC:1:25-1:100 |
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ALOX5 Antibody |
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| 35564-100ul | SAB | 100ul | EUR 252 |
ALOX5 antibody |
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| 38389-100ul | SAB | 100ul | EUR 252 |
 Alox5/ Rat Alox5 ELISA Kit |
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| ELI-04466r | Lifescience Market | 96 Tests | EUR 886 |
) ALOX5 antibody (Ser523) |
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| 70R-34631 | Fitzgerald | 100 ug | EUR 327 |
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Description: Purified Rabbit polyclonal ALOX5 antibody (Ser523) |
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) ALOX5 antibody (Ser271) |
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| 70R-33362 | Fitzgerald | 100 ug | EUR 327 |
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Description: Rabbit polyclonal ALOX5 antibody (Ser271) |
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 Anti-ALOX5 Antibody |
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| A1747-100 | Biovision | EUR 479 | |
ALOX5 antibody (Ser523) |
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| 70R-14936 | Fitzgerald | 100 ul | EUR 392 |
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Description: Rabbit polyclonal ALOX5 antibody (Ser523) |
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 Antibody) ALOX5 (pS271) Antibody |
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| 20-abx123322 | Abbexa |
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 Antibody) ALOX5 (pS523) Antibody |
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| abx012014-100ug | Abbexa | 100 ug | EUR 439 |
 ALOX5 Polyclonal Antibody |
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| A58062 | EpiGentek | 100 µg | EUR 570.55 |
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Description: Ask the seller for details |
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 Antibody) ALOX5 (pS663) Antibody |
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| abx148138-100ug | Abbexa | 100 ug | EUR 439 |
 Anti-ALOX5 antibody |
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| STJ22592 | St John's Laboratory | 100 µl | EUR 277 |
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Description: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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 ALOX5 Conjugated Antibody |
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| C35564 | SAB | 100ul | EUR 397 |
 ALOX5 siRNA |
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| 20-abx900294 | Abbexa |
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ALOX5 siRNA |
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| 20-abx907323 | Abbexa |
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ALOX5 siRNA |
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| 20-abx907324 | Abbexa |
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 Antibody) Phospho-ALOX5(Ser523) Antibody |
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| AF0064 | Affbiotech | 200ul | EUR 304 |
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Description: Phospho-ALOX5(Ser523) Antibody detects endogenous levels of ALOX5 only when phosphorylated at Sersine 523. |
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 Antibody) Phospho-ALOX5 (Ser663) Antibody |
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| AF8359 | Affbiotech | 200ul | EUR 376 |
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Description: ALOX5 (Phospho-Ser663) Antibody detects endogenous levels of ALOX5 only when phosphorylated at Ser663. |
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 Antibody) ALOX5 (Phospho- Ser663) Antibody |
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| ABF8359 | Lifescience Market | 100 ug | EUR 438 |
 Antibody) Phospho- ALOX5 (Ser523) Antibody |
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| ABF0064 | Lifescience Market | 100 ug | EUR 438 |
 Antibody) Phospho-ALOX5 (Ser523) Antibody |
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| A1714-100 | Biovision | EUR 479 | |
Phospho-ALOX5 (Ser523) Antibody |
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| CSB-PA555261- | Cusabio | EUR 335 | |
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Description: A polyclonal antibody against Phospho-ALOX5 (Ser523). Recognizes Phospho-ALOX5 (Ser523) from Human, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000 |
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Phospho-ALOX5 (Ser523) Antibody |
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| CSB-PA555261-100ul | Cusabio | 100ul | EUR 362 |
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Description: A polyclonal antibody against Phospho-ALOX5 (Ser523). Recognizes Phospho-ALOX5 (Ser523) from Human, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000 |
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 Antibody) Phospho-ALOX5 (S523) Antibody |
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| 1-CSB-PA008470 | Cusabio |
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Description: A polyclonal antibody against Phospho-ALOX5 (S523). Recognizes Phospho-ALOX5 (S523) from Human, Rat. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/10000 |
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 Antibody) Phospho-ALOX5 (S272) Antibody |
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| 1-CSB-PA008472 | Cusabio |
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Description: A polyclonal antibody against Phospho-ALOX5 (S272). Recognizes Phospho-ALOX5 (S272) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/10000 |
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 ALOX5 Antibody, HRP conjugated |
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| 1-CSB-PA001624LB01HU | Cusabio |
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Description: A polyclonal antibody against ALOX5. Recognizes ALOX5 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA |
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 ALOX5 Antibody, FITC conjugated |
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| 1-CSB-PA001624LC01HU | Cusabio |
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Description: A polyclonal antibody against ALOX5. Recognizes ALOX5 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA |
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 ALOX5 Antibody, Biotin conjugated |
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| 1-CSB-PA001624LD01HU | Cusabio |
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Description: A polyclonal antibody against ALOX5. Recognizes ALOX5 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA |
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 Antibody) ALOX5 (Phospho-Ser523) Antibody |
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| 12128-100ul | SAB | 100ul | EUR 252 |
ALOX5 (Phospho-Ser523) Antibody |
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| 12128-50ul | SAB | 50ul | EUR 187 |
 Antibody) ALOX5 (Phospho-Ser663) Antibody |
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| 12671-100ul | SAB | 100ul | EUR 252 |
ALOX5 (Phospho-Ser663) Antibody |
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| 12671-50ul | SAB | 50ul | EUR 187 |
 ALOX5 Blocking Peptide |
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| DF6881-BP | Affbiotech | 1mg | EUR 195 |
 pDONR223-ALOX5 Plasmid |
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| PVTB01075-1 | Lifescience Market | 2 ug | EUR 356 |
 ALOX5 cloning plasmid |
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| CSB-CL001624HU1-10ug | Cusabio | 10ug | EUR 677 |
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Description: A cloning plasmid for the ALOX5 gene. |
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ALOX5 cloning plasmid |
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| CSB-CL001624HU2-10ug | Cusabio | 10ug | EUR 474 |
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Description: A cloning plasmid for the ALOX5 gene. |
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 ALOX5 Rabbit pAb |
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| A2158-100ul | Abclonal | 100 ul | EUR 308 |
ALOX5 Rabbit pAb |
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| A2158-200ul | Abclonal | 200 ul | EUR 459 |
ALOX5 Rabbit pAb |
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| A2158-20ul | Abclonal | 20 ul | EUR 183 |
ALOX5 Rabbit pAb |
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| A2158-50ul | Abclonal | 50 ul | EUR 223 |
 Anti-5 Lipoxygenase/ALOX5 Antibody |
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| PA1644 | BosterBio | 100ug/vial | EUR 334 |
 Antibody) Arachidonate-5-Lipoxygenase (ALOX5) Antibody |
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| 20-abx128567 | Abbexa |
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Arachidonate-5-Lipoxygenase (ALOX5) Antibody |
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| 20-abx111039 | Abbexa |
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Arachidonate-5-Lipoxygenase (ALOX5) Antibody |
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| 20-abx102800 | Abbexa |
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Arachidonate-5-Lipoxygenase (ALOX5) Antibody |
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| 20-abx102801 | Abbexa |
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Arachidonate-5-Lipoxygenase (ALOX5) Antibody |
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| 20-abx102802 | Abbexa |
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 Antibody) Arachidonate 5-Lipoxygenase (ALOX5) Antibody |
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| 20-abx001770 | Abbexa |
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 ALOX5 Polyclonal Antibody, Biotin Conjugated |
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| A58063 | EpiGentek | 100 µg | EUR 570.55 |
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Description: The best epigenetics products |
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 ALOX5 Polyclonal Antibody, FITC Conjugated |
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| A58064 | EpiGentek | 100 µg | EUR 570.55 |
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Description: kits suitable for this type of research |
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 ALOX5 Polyclonal Antibody, HRP Conjugated |
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| A58065 | EpiGentek | 100 µg | EUR 570.55 |
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Description: fast delivery possible |
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Arachidonate-5-Lipoxygenase (ALOX5) Antibody |
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| 20-abx171312 | Abbexa |
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Arachidonate-5-Lipoxygenase (ALOX5) Antibody |
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| 20-abx171313 | Abbexa |
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Arachidonate 5-Lipoxygenase (ALOX5) Antibody |
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| 20-abx301130 | Abbexa |
|
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Arachidonate-5-Lipoxygenase (ALOX5) Antibody |
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| 20-abx242416 | Abbexa |
|
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Arachidonate-5-Lipoxygenase (ALOX5) Antibody |
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| 20-abx242434 | Abbexa |
|
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Arachidonate-5-Lipoxygenase (ALOX5) Antibody |
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| 20-abx175461 | Abbexa |
|
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 antibody) Anti-Phospho-ALOX5-(S271) antibody |
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| STJ29339 | St John's Laboratory | 100 µl | EUR 393 |
|
Description: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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Anti-5 Lipoxygenase/ALOX5 Antibody |
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| RP1031 | BosterBio | 100ug/vial | EUR 334 |
Arachidonate-5-Lipoxygenase (ALOX5) Antibody |
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| 20-abx328184 | Abbexa |
|
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 5-LOX/ALOX5/ Rat 5- LOX/ ALOX5 ELISA Kit |
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| ELA-E1355r | Lifescience Market | 96 Tests | EUR 886 |
 Human ALOX5 ELISA Kit |
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| ELA-E1355h | Lifescience Market | 96 Tests | EUR 824 |
 ALOX5 ELISA KIT|Human |
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| EF003791 | Lifescience Market | 96 Tests | EUR 689 |
) ALOX5 Recombinant Protein (Human) |
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| RP036568 | ABM | 100 ug | Ask for price |
ALOX5 Recombinant Protein (Human) |
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| RP036571 | ABM | 100 ug | Ask for price |
) ALOX5 Recombinant Protein (Mouse) |
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| RP115469 | ABM | 100 ug | Ask for price |
) ALOX5 Recombinant Protein (Rat) |
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| RP189989 | ABM | 100 ug | Ask for price |
 ALOX5 Cell ELISA Kit |
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| abx595027-96tests | Abbexa | 96 tests | EUR 637 |
 Rat ALOX5 shRNA Plasmid |
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| 20-abx984898 | Abbexa |
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 Human ALOX5 shRNA Plasmid |
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| 20-abx950167 | Abbexa |
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 Mouse ALOX5 shRNA Plasmid |
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| 20-abx969123 | Abbexa |
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 Mouse ALOX5 ELISA Kit |
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| STJ150547 | St John's Laboratory | 1 kit | EUR 412 |
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Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of 5-LO in Mouse serum, plasma and other biological fluids |
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 Antibody (HRP)) Arachidonate 5-Lipoxygenase (ALOX5) Antibody (HRP) |
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| 20-abx303049 | Abbexa |
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 Antibody (FITC)) Arachidonate 5-Lipoxygenase (ALOX5) Antibody (FITC) |
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| 20-abx303050 | Abbexa |
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 Antibody (Biotin)) Arachidonate 5-Lipoxygenase (ALOX5) Antibody (Biotin) |
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| 20-abx303051 | Abbexa |
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 Antibody (Biotin)) Arachidonate-5-Lipoxygenase (ALOX5) Antibody (Biotin) |
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| 20-abx272780 | Abbexa |
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 Polyclonal Conjugated Antibody) ALOX5 (Phospho-Ser523) Polyclonal Conjugated Antibody |
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| C12128 | SAB | 100ul | EUR 397 |
 Polyclonal Conjugated Antibody) ALOX5 (Phospho-Ser663) Polyclonal Conjugated Antibody |
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| C12671 | SAB | 100ul | EUR 397 |
 Polyclonal Antibody (Human)) Arachidonate-5-Lipoxygenase (ALOX5) Polyclonal Antibody (Human) |
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| 4-PAB355Hu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Arachidonate-5-Lipoxygenase (ALOX5) |
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 Polyclonal Antibody (Mouse)) Arachidonate-5-Lipoxygenase (ALOX5) Polyclonal Antibody (Mouse) |
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| 4-PAB355Mu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Arachidonate-5-Lipoxygenase (ALOX5) |
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Arachidonate-5-Lipoxygenase (ALOX5) Polyclonal Antibody (Mouse) |
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| 4-PAB355Mu02 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Arachidonate-5-Lipoxygenase (ALOX5) |
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 Monoclonal Antibody (Human)) Arachidonate-5-Lipoxygenase (ALOX5) Monoclonal Antibody (Human) |
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| 4-MAB355Hu21 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Arachidonate-5-Lipoxygenase (ALOX5) |
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) Polyclonal ALOX5 / 5-Lipoxygenase Antibody (aa130-149) |
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| APG01826G | Leading Biology | 1 ea | EUR 484 |
|
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ALOX5 / 5-Lipoxygenase (aa130-149). This antibody is tested and proven to work in the following applications: |
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) Polyclonal ALOX5 / 5-Lipoxygenase Antibody (aa246-295) |
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| APG01827G | Leading Biology | 0.05ml | EUR 484 |
|
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ALOX5 / 5-Lipoxygenase (aa246-295). This antibody is tested and proven to work in the following applications: |
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 Blocking Peptide) Phospho-ALOX5(Ser523) Blocking Peptide |
|||
| AF0064-BP | Affbiotech | 1mg | EUR 195 |
 Blocking Peptide) Phospho-ALOX5 (Ser663) Blocking Peptide |
|||
| AF8359-BP | Affbiotech | 1mg | EUR 195 |
) Recombinant Arachidonate-5-Lipoxygenase (ALOX5) |
|||
| 4-RPB355Hu01 | Cloud-Clone |
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Description: Recombinant Human Arachidonate-5-Lipoxygenase expressed in: E.coli |
|||
Recombinant Arachidonate-5-Lipoxygenase (ALOX5) |
|||
| 4-RPB355Mu01 | Cloud-Clone |
|
|
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Description: Recombinant Mouse Arachidonate-5-Lipoxygenase expressed in: E.coli |
|||
Recombinant Arachidonate-5-Lipoxygenase (ALOX5) |
|||
| 4-RPB355Mu02 | Cloud-Clone |
|
|
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Description: Recombinant Mouse Arachidonate-5-Lipoxygenase expressed in: E.coli |
|||
Recombinant Arachidonate-5-Lipoxygenase (ALOX5) |
|||
| 4-RPB355Ra01 | Cloud-Clone |
|
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Description: Recombinant Rat Arachidonate-5-Lipoxygenase expressed in: E.coli |
|||
 (pORF)) Alox5 ORF Vector (Rat) (pORF) |
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| ORF063331 | ABM | 1.0 ug DNA | EUR 506 |
 (pORF)) ALOX5 ORF Vector (Human) (pORF) |
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| ORF012190 | ABM | 1.0 ug DNA | EUR 354 |
ALOX5 ORF Vector (Human) (pORF) |
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| ORF012191 | ABM | 1.0 ug DNA | EUR 354 |
 (pORF)) Alox5 ORF Vector (Mouse) (pORF) |
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| ORF038491 | ABM | 1.0 ug DNA | EUR 506 |
 pECMV-Alox5-m-FLAG Plasmid |
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| PVT14943 | Lifescience Market | 2 ug | EUR 325 |
 Phospho-ALOX5-S271 Rabbit pAb |
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| AP0573-100ul | Abclonal | 100 ul | EUR 384 |
Phospho-ALOX5-S271 Rabbit pAb |
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| AP0573-200ul | Abclonal | 200 ul | EUR 554 |
Phospho-ALOX5-S271 Rabbit pAb |
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| AP0573-20ul | Abclonal | 20 ul | EUR 183 |
Phospho-ALOX5-S271 Rabbit pAb |
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| AP0573-50ul | Abclonal | 50 ul | EUR 265 |
 (OKEH04835)) Alox5 ELISA Kit (Rat) (OKEH04835) |
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| OKEH04835 | Aviva Systems Biology | 96 Wells | EUR 740 |
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Description: Description of target: Catalyzes the conversion of arachidonate to leukotriene A4 in leukotriene metabolism.;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.088 ng/mL |
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 (OKCD07350)) ALOX5 ELISA Kit (Mouse) (OKCD07350) |
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| OKCD07350 | Aviva Systems Biology | 96 Wells | EUR 818 |
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Description: Description of target: Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 0.065ng/mL |
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 (OKAN05523)) ALOX5 ELISA Kit (Mouse) (OKAN05523) |
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| OKAN05523 | Aviva Systems Biology | 96 Wells | EUR 792 |
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Description: Description of target: ;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.065 ng/mL |
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 Polyclonal Antibody (Human), APC) Arachidonate-5-Lipoxygenase (ALOX5) Polyclonal Antibody (Human), APC |
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| 4-PAB355Hu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Arachidonate-5-Lipoxygenase (ALOX5). This antibody is labeled with APC. |
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 Polyclonal Antibody (Human), Biotinylated) Arachidonate-5-Lipoxygenase (ALOX5) Polyclonal Antibody (Human), Biotinylated |
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| 4-PAB355Hu01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Arachidonate-5-Lipoxygenase (ALOX5). This antibody is labeled with Biotin. |
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 Polyclonal Antibody (Human), Cy3) Arachidonate-5-Lipoxygenase (ALOX5) Polyclonal Antibody (Human), Cy3 |
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| 4-PAB355Hu01-Cy3 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Arachidonate-5-Lipoxygenase (ALOX5). This antibody is labeled with Cy3. |
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 Polyclonal Antibody (Human), FITC) Arachidonate-5-Lipoxygenase (ALOX5) Polyclonal Antibody (Human), FITC |
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| 4-PAB355Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Arachidonate-5-Lipoxygenase (ALOX5). This antibody is labeled with FITC. |
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 Polyclonal Antibody (Human), HRP) Arachidonate-5-Lipoxygenase (ALOX5) Polyclonal Antibody (Human), HRP |
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| 4-PAB355Hu01-HRP | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Arachidonate-5-Lipoxygenase (ALOX5). This antibody is labeled with HRP. |
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 Polyclonal Antibody (Human), PE) Arachidonate-5-Lipoxygenase (ALOX5) Polyclonal Antibody (Human), PE |
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| 4-PAB355Hu01-PE | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Arachidonate-5-Lipoxygenase (ALOX5). This antibody is labeled with PE. |
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 Polyclonal Antibody (Mouse), APC) Arachidonate-5-Lipoxygenase (ALOX5) Polyclonal Antibody (Mouse), APC |
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| 4-PAB355Mu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Arachidonate-5-Lipoxygenase (ALOX5). This antibody is labeled with APC. |
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 Polyclonal Antibody (Mouse), Biotinylated) Arachidonate-5-Lipoxygenase (ALOX5) Polyclonal Antibody (Mouse), Biotinylated |
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| 4-PAB355Mu01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Arachidonate-5-Lipoxygenase (ALOX5). This antibody is labeled with Biotin. |
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 Polyclonal Antibody (Mouse), Cy3) Arachidonate-5-Lipoxygenase (ALOX5) Polyclonal Antibody (Mouse), Cy3 |
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| 4-PAB355Mu01-Cy3 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Arachidonate-5-Lipoxygenase (ALOX5). This antibody is labeled with Cy3. |
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 Polyclonal Antibody (Mouse), FITC) Arachidonate-5-Lipoxygenase (ALOX5) Polyclonal Antibody (Mouse), FITC |
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| 4-PAB355Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Arachidonate-5-Lipoxygenase (ALOX5). This antibody is labeled with FITC. |
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 Polyclonal Antibody (Mouse), HRP) Arachidonate-5-Lipoxygenase (ALOX5) Polyclonal Antibody (Mouse), HRP |
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| 4-PAB355Mu01-HRP | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Arachidonate-5-Lipoxygenase (ALOX5). This antibody is labeled with HRP. |
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 Polyclonal Antibody (Mouse), PE) Arachidonate-5-Lipoxygenase (ALOX5) Polyclonal Antibody (Mouse), PE |
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| 4-PAB355Mu01-PE | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Arachidonate-5-Lipoxygenase (ALOX5). This antibody is labeled with PE. |
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Arachidonate-5-Lipoxygenase (ALOX5) Polyclonal Antibody (Mouse), APC |
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| 4-PAB355Mu02-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Arachidonate-5-Lipoxygenase (ALOX5). This antibody is labeled with APC. |
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Arachidonate-5-Lipoxygenase (ALOX5) Polyclonal Antibody (Mouse), Biotinylated |
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| 4-PAB355Mu02-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Arachidonate-5-Lipoxygenase (ALOX5). This antibody is labeled with Biotin. |
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Arachidonate-5-Lipoxygenase (ALOX5) Polyclonal Antibody (Mouse), Cy3 |
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| 4-PAB355Mu02-Cy3 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Arachidonate-5-Lipoxygenase (ALOX5). This antibody is labeled with Cy3. |
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